Product Number |
OAAB16065 |
Product Page |
www.avivasysbio.com/mecp2-antibody-phospho-s292-oaab16065.html |
Name |
MECP2 Antibody (Phospho-Ser292) (OAAB16065) |
Molecular Weight |
52441 Da |
Isotype |
Ig |
NCBI Gene Id |
4204 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
RS, RTS, RTT, PPMX, MRX16, MRX79, MRXSL, AUTSX3, MRXS13 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB16065 |
Additional Information |
Precautions: Phospho-MECP2-pS292 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A |
Application Info |
IHC-P: 1:50~100 |
Immunogen |
This MECP2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S292 of human MECP2. |
Additional Information |
Cellular Location: Nucleus. Note=Colocalized with methyl-CpG in the genome Tissue Location: Present in all adult somatic tissues tested. |
Uniprot ID |
P51608 |
Protein Name |
Methyl-CpG-binding protein 2 |
Protein Accession # |
NP_001104262.1 |
Gene Symbol |
MECP2 |
Predicted Species Reactivity |
Human |
Application |
IHC |
Predicted Homology Based on Immunogen Sequence |
Human |
Image 1 | breast carcinoma
| Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
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