|Mouse Enpp1 Antibody - N-terminal region (OAAB15252)
|Enpp1, Npps, Pc1, Pdnp1, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, Lymphocyte antigen 41, Phosphodiesterase I/nucleotide pyrophosphatase 1, Plasma-cell membrane glycoprotein PC-1, Alkaline phosphodiesterase I, Nucleotide p
|LiquidPBS with 0.09% (W/V) sodium azide.
|Description of Target
|Involved primarily in ATP hydrolysis at the plasma membrane. Plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. In vitro, has a broad specificity, hydrolyzing other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity
|Reconstitution and Storage
|Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
|Printable datasheet for OAAB15252
|Cellular Location: Membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Note=Targeted to the basolateral membrane in polarized epithelial cells and in hepatocytes, and to matrix vesicles in osteoblasts. In bile duct cells and cancer cells, located to the apical cytoplasmic side
Tissue Location: Selectively expressed on the surface of antibody-secreting cells
|This Mouse Enpp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of mouse Enpp1.
|Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
|This antibody is purified through a protein A column, followed by peptide affinity purification.
|Predicted Species Reactivity
|Mouse Enpp1 Antibody (N-term) (Cat. # OAAB15252) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Mouse Enpp1 antibody detected the Mouse Enpp1 protein (arrow).