| Product Number |
OAAB09635 |
| Product Page |
www.avivasysbio.com/apoo-antibody-n-terminal-region-oaab09635.html |
| Name |
APOO Antibody - N-terminal region (OAAB09635) |
| Molecular Weight |
22285 Da |
| Isotype |
Ig |
| NCBI Gene Id |
79135 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Description |
|
| Alias Symbols |
MIC26, Mic23, My025, FAM121B, MICOS26 |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB09635 |
| Additional Information |
Precautions: APOO Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation |
| Application Info |
WB: 1:1000
IHC-P: 1:10~50 |
| Immunogen |
This APOO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human APOO. |
| Additional Information |
Cellular Location: Membrane; Single-pass membrane protein (Potential). Secreted
Tissue Location: Expressed in all tissues examined. Up- regulated in diabetic heart |
| Uniprot ID |
Q9BUR5 |
| Protein Name |
Apolipoprotein O |
| Publications |
Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv. 3, e1700677 (2017). 28835921 |
| Sample Type Confirmation |
APOO is strongly supported by BioGPS gene expression data to be expressed in K562 |
| Protein Accession # |
NP_077027.1 |
| Gene Symbol |
APOO |
| Predicted Species Reactivity |
Human |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | K562
 | APOO Antibody (N-term ) (Cat. #OAAB09635) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APOO antibody detected the APOO protein (arrow). APOO is strongly supported by BioGPS gene expression data to be expressed in K562 |
|
| Image 2 | Human Heart
 | APOO Antibody (N-term) (Cat. #OAAB09635)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of APOO Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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