FASTK Antibody - C-terminal region (OAAB08734)

• Product Number: OAAB08734
• Name: FASTK Antibody - C-terminal region (OAAB08734)
• Molecular Weight: 61104 Da
• Isotype: Ig
• NCBI Gene Id: 10922
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: FAST
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: FASTK Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor
• Application Info: WB: 1:1000
  IHC-P: 1:10~50
• Immunogen: This FASTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human FASTK.
• Additional Information: Tissue Location: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
• Uniprot ID: Q14296
• Protein Name: Fas-activated serine/threonine kinase
• Publications:

  Bauer, A. et al. Identification of malignancy factors by analyzing cystic tumors of the pancreas. Pancreatology 9, 34-44 (2009). 19077453

• Sample Type Confirmation:

  There is BioGPS gene expression data showing that FASTK is expressed in HEK293

• Protein Accession #: NP_006703.1
• Gene Symbol: FASTK
• Predicted Species Reactivity: Human
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: Human Liver
  
  FASTK Antibody (C-term) (Cat. #OAAB08734)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FASTK Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
• Image 2: 293
  
  Western blot analysis of FASTK (arrow) using rabbit polyclonal FASTK Antibody (C-term) (Cat. #OAAB08734). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FASTK gene.

  There is BioGPS gene expression data showing that FASTK is expressed in HEK293