| Product Number |
OAAB06622 |
| Product Page |
www.avivasysbio.com/phospho-mbad-ser155-antibody-oaab06622.html |
| Name |
mBad Antibody (Phospho-Ser155) (OAAB06622) |
| Molecular Weight |
22080 Da |
| Clone |
27AT937 |
| Isotype |
IgG1 |
| NCBI Gene Id |
12015 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
Bbc2, AI325008 |
| Product Format |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Description of Target |
Purified Phospho-specific Monoclonal Antibody (Mab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB06622 |
| Additional Information |
Precautions: Phospho-mBad-Ser155 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 Appears to act as a link between growth factor receptor signaling and the apoptotic pathways |
| Application Info |
WB: 1:100~500 |
| Immunogen |
This mouse Bad Antibody is generated from mice immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Ser155 of mouse Bad. |
| Additional Information |
Cellular Location: Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm |
| Uniprot ID |
Q61337 |
| Protein Name |
Bcl2 antagonist of cell death |
| Protein Accession # |
NP_031548.1 |
| Gene Symbol |
Bad |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
| Image 1 | |
|
