LMX1B Antibody - middle region (OAAB05531)

• Product Number: OAAB05531
• Name: LMX1B Antibody - middle region (OAAB05531)
• Molecular Weight: 44917
• Isotype: Rabbit Ig
• NCBI Gene Id: 16917|396312|399182|4010
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: FSGS10, GENA 191, homeobox protein LMX-1, homeodomain protein (lmx), Ic, Icst, LIM homeo box transcription factor 1B, LIM homeobox protein, LIM homeobox protein 1b, LIM homeobox transcription factor 1-beta, LIM homeobox transcription factor 1-beta.1, LIM/homeobox protein 1, LIM/homeobox protein 1.2, LIM/homeobox protein LMX-1.2, LIM/homeobox protein LMX1B, LMX, LMX-1.2, LMX1, LMX1., LMX1.1, LMX1.2, lmx1b, lmx1b.1, NPS1, XELAEV_18041790mg, Xlmx1b.
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Description of Target: Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.|Required for early specification of the kidney glomus, lying upstream of wt1 in the pathway controlling glomus differentiation. The balance in levels and expression patterns of binding partners such as lhx1/lim-1 influences differentiation into glomus or tubule derivatives. Involved in specification of serotonergic neurons.|Specifies dorsal cell fate during limb development.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This LMX1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the Central region of human LMX1B.
• Uniprot ID: O60663|O88609|P53413|Q8UVR3
• Protein Name: LIM homeobox transcription factor 1-beta|LIM homeobox transcription factor 1-beta isoform 1 [Homo sapiens]|LIM homeobox transcription factor 1-beta isoform 2 [Homo sapiens]|LIM homeobox transcription factor 1-beta.1|LIM/homeobox protein LMX-1.2
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001167618.1,NP_002307.2
• Gene Symbol: LMX1B
• Predicted Species Reactivity: Chicken|Human|Mouse|Xenopus
• Application: IHC-P,WB
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Image 1: Mouse Heart
  
  Western blot analysis of LMX1B Antibody (Center) in mouse heart tissue lysates (35ug/lane). LMX1B (arrow) was detected using the purified Pab.
• Image 2: LMX1B
  
  Western blot analysis of LMX1B (arrow) using rabbit polyclonal LMX1B Antibody (Center) either nontransfected (Lane 1) or lysates transiently transfected transfected (Lane 2) with the LMX1B gene.
• Image 3: Human Testis
  
  Formalin-fixed and paraffin-embedded human testis tissue reacted with LMX1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.