CCR3 Antibody - middle region (OAAB05403)

Data Sheet
 
Product Number OAAB05403
Product Page www.avivasysbio.com/ccr3-antibody-center-region-oaab05403.html
Name CCR3 Antibody - middle region (OAAB05403)
Molecular Weight 41044
Isotype Rabbit Ig
NCBI Gene Id 1232
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name C-C motif chemokine receptor 3
Alias Symbols b-chemokine receptor;C C CKR3;CC chemokine receptor 3;C-C chemokine receptor type 3;C-C CKR-3;CC-CKR-3;CCR-3;CD193;chemokine (C-C motif) receptor 3;CKR 3;CKR3;CMKBR3;eosinophil CC chemokine receptor 3;eosinophil eotaxin receptor.
Product Format Liquid PBS with 0.09% (W/V) sodium azide.
Description of Target C-C chemokine receptor type 3, C-C chemokine receptor type 3 isoform 1 [Homo sapiens], C-C chemokine receptor type 3 isoform 2 [Homo sapiens]
Reconstitution and Storage Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for CCR3 Antibody (Center) (OAAB05403)
Additional Information Cellular Location: Cell membrane; Multi-pass membrane protein.
Tissue Location: In eosinophils as well as trace amounts in neutrophils and monocytes.
Application Info WB: 1:1000
FC: 1:10~50
Other Applications Image 1 Data CCR3 Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Immunogen This CCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3.
Uniprot ID https://www.uniprot.org/uniprot/?query=P51677+OR+Q9BDS8
Protein Name NP_001828.1, NP_847898.1, NP_847899.1, P51677, Q9BDS8
Publications

Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils. PLoS ONE. 11, e0157186 (2016). 27275740

Protein Accession # https://www.ncbi.nlm.nih.gov/protein/NP_001828.1,NP_847898.1,NP_847899.1
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Gene Symbol CCR3
Predicted Species Reactivity Human, Primate
Application Flow cytometry, Western blot
Predicted Homology Based on Immunogen Sequence Human
Image 1
Jurkat
Western blot analysis of CCR3 Antibody (Center) in Jurkat cell lysates (35ug/lane). CCR3 (arrow) was detected using the purified Pab.
Image 2
Jurkat
CCR3 Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
 

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