CSN1S1 Antibody - middle region (OAAB03556)

• Product Number: OAAB03556
• Name: CSN1S1 Antibody - middle region (OAAB03556)
• Molecular Weight: 22 kDa
• Isotype: Rabbit Ig
• NCBI Gene Id: 1446
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Varies by lot. See vial for concentration.
• Alias Symbols: CASA, CSN1
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Description of Target: CASA play an important role in the capacity of milk to transport calcium phosphate. Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1 receptors.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Function: Important role in the capacity of milk to transport calcium phosphate.
  Cellular Location: Secreted
  Tissue Location: Mammary gland specific; secreted in milk.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: CASA Antibody (Center) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
• Immunogen: This CASA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the Central region of human CASA.
• Uniprot ID: P47710
• Protein Name: Alpha-S1-casein
• Publications:

  Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996

• Protein Accession #: NP_001020275.1
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Gene Symbol: CSN1S1
• Predicted Species Reactivity: Human
• Application: WB, IHC-P, FC
• Image 1: Jurkat
  
  Western blot analysis of CASA antibody (Center) in Jurkat cell lysates (35ug/lane). CASA (arrow) was detected using the purified Pab.
• Image 2: human brain carcinoma
  
  CASA Antibody (Center) (RB18742) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CASA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
• Image 3: MCF-7
  
  CASA Antibody (Center) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.