| Product Number |
OAAB02444 |
| Product Page |
www.avivasysbio.com/fbxl2-antibody-c-terminal-region-oaab02444.html |
| Name |
FBXL2 Antibody - C-terminal region (OAAB02444) |
| Molecular Weight |
47062 |
| Isotype |
Ig |
| NCBI Gene Id |
25827 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Varies by lot. See vial for concentration. |
| Gene Full Name |
F-box and leucine rich repeat protein 2 |
| Description |
|
| Alias Symbols |
FBL2;FBL3;F-box and leucine-rich repeat protein 2;F-box protein containing leucine-rich repeats;F-box protein FBL2/FBL3;F-box/LRR-repeat protein 2. |
| Product Format |
Liquid.PBS with 0.09% (W/V) sodium azide |
| Reference |
Ye, J. PLoS Pathog. 3 (8), E108 (2007)
Ilyin, G.P., et al. Genomics 67(1):40-47(2000)
Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999) |
| Description of Target |
F-box/LRR-repeat protein 2, F-box/LRR-repeat protein 2 isoform 1 [Homo sapiens], F-box/LRR-repeat protein 2 isoform 2 [Homo sapiens] |
| Reconstitution and Storage |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for FBXL2 Antibody (C-term) (OAAB02444) |
| Additional Information |
Cellular Location: Membrane; Lipid-anchor.
Tissue Location: Expressed in brain, heart, kidney, liver, lung, pancreas and placenta. |
| Application Info |
WB: 1:1000~1:2000
IHC-P: 1:50~100
FC: 1:10~50
Optimal dilutions should be determined by the end user. |
| Immunogen |
This FBXL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-395 amino acids from the C-terminal region of human FBXL2. |
| Intended Use |
For research use only and not for use in diagnostic or therapeutic procedures. |
| Uniprot ID |
https://www.uniprot.org/uniprot/?query=Q8BH16+OR+Q9UKC9 |
| Protein Name |
NP_001165184.1, NP_036289.3, Q8BH16, Q9UKC9 |
| Publications |
Crystal structure and interaction studies of the human FBxo3 ApaG domain. FEBS J. 283, 2091-101 (2016). 27010866 |
| Protein Accession # |
https://www.ncbi.nlm.nih.gov/protein/NP_001165184.1,NP_036289.3 |
| Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Tested Species Reactivity |
Human |
| Gene Symbol |
FBXL2 |
| Predicted Species Reactivity |
Human, Mouse |
| Application |
Flow cytometry, Immunohistochemistry-Paraffin, Western blot |
| Image 1 | human lung carcinoma
 | FBXL2 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
|
| Image 2 | MDA-MB435
 | FBXL2 Antibody (C-term) (Cat. #OAAB02444) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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