| Product Number |
AVARP13086_T100-FITC |
| Product Page |
www.avivasysbio.com/gdi1-antibody-c-terminal-region-fitc-avarp13086-t100-fitc.html |
| Name |
GDI1 Antibody - C-terminal region : FITC (AVARP13086_T100-FITC) |
| Protein Size (# AA) |
447 amino acids |
| Molecular Weight |
51kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
2664 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
GDP dissociation inhibitor 1 |
| Alias Symbols |
1A, GDIL, MRX41, MRX48, OPHN2, XAP-4, RABGD1A, RABGDIA |
| Peptide Sequence |
Synthetic peptide located within the following region: VFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
Papaharalambus,C., et al., (2005) J. Biol. Chem. 280 (19), 18790-18796 |
| Description of Target |
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. |
| Protein Interactions |
LNX1; UBC; RCC2; DCUN1D1; ACOT7; GGH; HIST1H2BO; SGTA; NEDD8; HEXA; GNAI2; ASL; ALDH9A1; SCRN1; GINS3; IQCB1; GNL1; RAB11B; RAB1A; PCMT1; UBQLN4; CUL5; CDK2; SIRT7; MINOS1; TK1; RAB24; RAB1B; RABAC1; RAB27A; RAC2; RHOH; RAB9A; RAB6A; EPB41; CDC42; PSEN1; |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-GDI1 (AVARP13086_T100-FITC) antibody |
| Blocking Peptide |
For anti-GDI1 (AVARP13086_T100-FITC) antibody is Catalog # AAP30750 (Previous Catalog # AAPP01411) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GDI1 |
| Uniprot ID |
P31150 |
| Protein Name |
Rab GDP dissociation inhibitor alpha |
| Protein Accession # |
NP_001484 |
| Nucleotide Accession # |
NM_001493 |
| Gene Symbol |
GDI1 |
| Predicted Species Reactivity |
Human, Mouse, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Sheep: 92%; Zebrafish: 92% |
| Image 1 | |
