Product Number |
AVARP13059_P050 |
Product Page |
www.avivasysbio.com/apba1-antibody-n-terminal-region-avarp13059-p050.html |
Name |
APBA1 Antibody - N-terminal region (AVARP13059_P050) |
Protein Size (# AA) |
837 amino acids |
Molecular Weight |
93kDa |
NCBI Gene Id |
320 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Amyloid beta (A4) precursor protein-binding, family A, member 1 |
Alias Symbols |
X11, X11A, LIN10, MINT1, D9S411E, X11ALPHA |
Peptide Sequence |
Synthetic peptide located within the following region: PPQQQHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. |
Protein Interactions |
STXBP1; CNTNAP4; NRXN1; CNTNAP3; KIF17; LIN7B; KCNJ12; CCS; CACNA1B; HTR2C; CASK; NOTCH1; STX1A; APP; PSEN1; LIN7A; PSEN2; LIN7C; DLG1; APBB1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-APBA1 (AVARP13059_P050) antibody |
Blocking Peptide |
For anti-APBA1 (AVARP13059_P050) antibody is Catalog # AAP30656 (Previous Catalog # AAPP01313) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1 |
Uniprot ID |
Q02410 |
Protein Name |
Amyloid beta A4 precursor protein-binding family A member 1 |
Sample Type Confirmation |
APBA1 is supported by BioGPS gene expression data to be expressed in Raji |
Protein Accession # |
EAW62487 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001163 |
Tested Species Reactivity |
Human, Rat |
Gene Symbol |
APBA1 |
Predicted Species Reactivity |
Human |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Human: 100% |
Image 1 | Human Intestine
| Human Intestine |
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Image 2 | Rat hippocampal
| Sample Type: Rat Hippocampal Neurons - 14DIVPrimary Antibody Dilution: 1:200Secondary Antibody: Anti-rabbit-Cy3Secondary Antibody Dilution: 1:500Color/Signal Descriptions: White: APBA1Gene Name: APBA1Submitted by: Dan Fowler - University of Oregon, Institute of Neuroscience |
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Image 3 | Human Raji
| WB Suggested Anti-APBA1 Antibody Titration: 0.2-1 ug/ml Positive Control: Raji cell lysateAPBA1 is supported by BioGPS gene expression data to be expressed in Raji |
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