APBA1 Antibody - N-terminal region (AVARP13059_P050)

Data Sheet
 
Product Number AVARP13059_P050
Product Page www.avivasysbio.com/apba1-antibody-n-terminal-region-avarp13059-p050.html
Name APBA1 Antibody - N-terminal region (AVARP13059_P050)
Protein Size (# AA) 837 amino acids
Molecular Weight 93kDa
NCBI Gene Id 320
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Amyloid beta (A4) precursor protein-binding, family A, member 1
Alias Symbols X11, X11A, LIN10, MINT1, D9S411E, X11ALPHA
Peptide Sequence Synthetic peptide located within the following region: PPQQQHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTD
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Protein Interactions STXBP1; CNTNAP4; NRXN1; CNTNAP3; KIF17; LIN7B; KCNJ12; CCS; CACNA1B; HTR2C; CASK; NOTCH1; STX1A; APP; PSEN1; LIN7A; PSEN2; LIN7C; DLG1; APBB1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-APBA1 (AVARP13059_P050) antibody
Blocking Peptide For anti-APBA1 (AVARP13059_P050) antibody is Catalog # AAP30656 (Previous Catalog # AAPP01313)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1
Uniprot ID Q02410
Protein Name Amyloid beta A4 precursor protein-binding family A member 1
Sample Type Confirmation

APBA1 is supported by BioGPS gene expression data to be expressed in Raji

Protein Accession # EAW62487
Purification Affinity Purified
Nucleotide Accession # NM_001163
Tested Species Reactivity Human, Rat
Gene Symbol APBA1
Predicted Species Reactivity Human
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Human: 100%
Image 1
Human Intestine
Human Intestine
Image 2
Rat hippocampal
Sample Type:
Rat Hippocampal Neurons - 14DIV
Primary Antibody Dilution:
1:200
Secondary Antibody:
Anti-rabbit-Cy3
Secondary Antibody Dilution:
1:500
Color/Signal Descriptions:
White: APBA1
Gene Name:
APBA1
Submitted by:
Dan Fowler - University of Oregon, Institute of Neuroscience
Image 3
Human Raji
WB Suggested Anti-APBA1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Raji cell lysateAPBA1 is supported by BioGPS gene expression data to be expressed in Raji
 

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