| Product Number |
AVARP13050_P050 |
| Product Page |
www.avivasysbio.com/oprk1-antibody-n-terminal-region-avarp13050-p050.html |
| Name |
OPRK1 Antibody - N-terminal region (AVARP13050_P050) |
| Protein Size (# AA) |
380 amino acids |
| Molecular Weight |
43kDa |
| NCBI Gene Id |
4986 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Opioid receptor, kappa 1 |
| Alias Symbols |
KOP, KOR, KOR1, OPRK, KOR-1, K-OR-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: DSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Edenberg,H.J., (2008) Hum. Mol. Genet. 17 (12), 1783-1789 |
| Description of Target |
OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions. |
| Protein Interactions |
GPRASP1; GABARAPL1; SLC9A3R1; OPRD1; GNA15; UBC; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-OPRK1 (AVARP13050_P050) antibody |
| Blocking Peptide |
For anti-OPRK1 (AVARP13050_P050) antibody is Catalog # AAP30728 (Previous Catalog # AAPP01385) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human OPRK1 |
| Uniprot ID |
P41145 |
| Protein Name |
Kappa-type opioid receptor |
| Protein Accession # |
NP_000903 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000912 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
OPRK1 |
| Predicted Species Reactivity |
Human, Mouse, Guinea Pig, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 91%; Human: 100%; Mouse: 84%; Pig: 85% |
| Image 1 | Human Brain
 | WB Suggested Anti-OPRK1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain |
|
| Image 2 | Fetal Kidney
 | WB Suggested Anti-OPRK1 Antibody Titration: 1 ug/ml
Positive Control: HuFetal Kidney |
|
