HTR2A Antibody - N-terminal region (AVARP13044_P050)

• Product Number: AVARP13044_P050
• Name: HTR2A Antibody - N-terminal region (AVARP13044_P050)
• Protein Size (# AA): 471 amino acids
• Molecular Weight: 53 kDa
• NCBI Gene Id: 3356
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
• Alias Symbols: HTR2, 5-HT2A
• Peptide Sequence: Synthetic peptide located within the following region: DILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSEN
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Yoon,H.K. (er) Prog. Neuropsychopharmacol. Biol. Psychiatry (2008) In press
• Description of Target: HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
• Protein Interactions: LYN; CBL; NDUFB10; ANKS1B; MRPL28; EIF3F; DLG4; PON2; NME3; GNAQ; PPP5C; MAP1A; RPS6KA3; NTRK3; JAK2; GNA11; GNAI1; GLUL;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Enhanced Validation:

  WB	Y
  SPR
  YCHAROS

• Blocking Peptide: For anti-HTR2A (AVARP13044_P050) antibody is Catalog # AAP30715 (Previous Catalog # AAPP01372)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2A
• Uniprot ID: P28223
• Protein Name: 5-hydroxytryptamine receptor 2A
• Sample Type Confirmation:

  HTR2A is supported by BioGPS gene expression data to be expressed in 721_B

• Protein Accession #: NP_000612
• Purification: Affinity Purified
• Nucleotide Accession #: NM_000621
• Tested Species Reactivity: Human
• Gene Symbol: HTR2A
• Predicted Species Reactivity: Human, Mouse, Pig
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Mouse: 78%; Pig: 92%
• Image 1: Human 721_B
  
  WB Suggested Anti-HTR2A Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:312500
  Positive Control: 721_B cell lysateHTR2A is supported by BioGPS gene expression data to be expressed in 721_B