| Product Number |
AVARP09007_P050 |
| Product Page |
www.avivasysbio.com/rgs3-antibody-c-terminal-region-avarp09007-p050.html |
| Name |
RGS3 Antibody - C-terminal region (AVARP09007_P050) |
| Protein Size (# AA) |
917 amino acids |
| Molecular Weight |
101kDa |
| NCBI Gene Id |
5998 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Regulator of G-protein signaling 3 |
| Alias Symbols |
C2PA, RGP3 |
| Peptide Sequence |
Synthetic peptide located within the following region: KDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSPPL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Yau,D.M., (2008) Mol. Pharmacol. 73 (5), 1356-1361 |
| Description of Target |
RGS3 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known. |
| Protein Interactions |
GORASP2; UBC; PLSCR1; SUMO2; HES4; GNAI2; GNA11; APP; ACD; ARRB1; Nedd4; IRF5; ISG15; CNKSR2; PAX6; GLS2; YWHAE; HIPK3; PARK2; MAPK12; RGS3; YWHAB; YWHAZ; EFNB2; SCN5A; EFNB1; YWHAQ; GNAI3; GRIN2A; ESR1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RGS3 (AVARP09007_P050) antibody |
| Specificity |
Isoforms 1-4 & 6 of P49796 |
| Blocking Peptide |
For anti-RGS3 (AVARP09007_P050) antibody is Catalog # AAP30212 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RGS3 |
| Uniprot ID |
P49796-4 |
| Protein Name |
Regulator of G-protein signaling 3 |
| Protein Accession # |
NP_570613 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_130795 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RGS3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100% |
| Image 1 | Human Heart
 | WB Suggested Anti-RGS3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human heart |
|
