CCR4 Antibody - middle region (AVARP07017_P050)

Data Sheet
 
Product Number AVARP07017_P050
Product Page www.avivasysbio.com/ccr4-antibody-middle-region-avarp07017-p050.html
Name CCR4 Antibody - middle region (AVARP07017_P050)
Protein Size (# AA) 360 amino acids
Molecular Weight 41kDa
NCBI Gene Id 1233
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Chemokine (C-C motif) receptor 4
Alias Symbols CKR4, K5-5, CD194, CMKBR4, ChemR13, CC-CKR-4, HGCN:14099
Peptide Sequence Synthetic peptide located within the following region: TERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Nakayama,T., (2008) Oncogene 27 (23), 3221-3232
Description of Target CCR4 belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1657 BC071751.1 1-1657
Protein Interactions CCL22; CCL17; CCL5; CCL3; ADRBK2; ADRBK1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CCR4 (AVARP07017_P050) antibody
Blocking Peptide For anti-CCR4 (AVARP07017_P050) antibody is Catalog # AAP30786 (Previous Catalog # AAPP01449)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CCR4
Uniprot ID P51679
Protein Name C-C chemokine receptor type 4
Sample Type Confirmation

CCR4 is supported by BioGPS gene expression data to be expressed in 721_B

Protein Accession # NP_005499
Purification Affinity Purified
Nucleotide Accession # NM_005508
Tested Species Reactivity Human
Gene Symbol CCR4
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 87%; Dog: 87%; Human: 100%; Mouse: 87%; Rat: 87%
Image 1
Human 721_B
WB Suggested Anti-CCR4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysateCCR4 is supported by BioGPS gene expression data to be expressed in 721_B
 

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