| Product Number |
AVARP03041_P050 |
| Product Page |
www.avivasysbio.com/cdc25b-antibody-n-terminal-region-avarp03041-p050.html |
| Name |
CDC25B Antibody - N-terminal region (AVARP03041_P050) |
| Protein Size (# AA) |
580 amino acids |
| Molecular Weight |
65kDa |
| NCBI Gene Id |
994 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Cell division cycle 25 homolog B (S. pombe) |
| Peptide Sequence |
Synthetic peptide located within the following region: MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Uchida,S., et al., (2004) Biochem. Biophys. Res. Commun. 316 (1), 226-232 |
| Description of Target |
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. |
| Protein Interactions |
BTRC; UBC; FBXW11; MAPK9; CDK5; CDK1; YWHAQ; MAPKAPK2; UBD; BRSK2; CDC14A; CDK2; Cdc25b; FOXM1; BRSK1; FHL3; KAT2B; MELK; YWHAE; CHEK1; AURKA; SFN; YWHAB; YWHAZ; MAPK14; CREBBP; AR; ESR1; CSNK2B; CSNK2A1; YWHAH; PGR; PHB2; KRT85; KRT35; KRT31; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CDC25B (AVARP03041_P050) antibody |
| Blocking Peptide |
For anti-CDC25B (AVARP03041_P050) antibody is Catalog # AAP30149 (Previous Catalog # AAPP00306) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25B |
| Uniprot ID |
P30305 |
| Protein Name |
M-phase inducer phosphatase 2 |
| Sample Type Confirmation |
CDC25B is supported by BioGPS gene expression data to be expressed in Daudi |
| Protein Accession # |
NP_068659 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_021873 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CDC25B |
| Predicted Species Reactivity |
Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 76%; Guinea Pig: 100%; Horse: 90%; Pig: 92%; Rabbit: 84% |
| Image 1 | Human Daudi
 | WB Suggested Anti-CDC25B Antibody Titration: 0.2-1 ug/ml
Positive Control: Daudi cell lysateCDC25B is supported by BioGPS gene expression data to be expressed in Daudi |
|
| Image 2 | Human Liver
 | Human Liver |
|
