CDC25B Antibody - N-terminal region (AVARP03041_P050)

Data Sheet
 
Product Number AVARP03041_P050
Product Page www.avivasysbio.com/cdc25b-antibody-n-terminal-region-avarp03041-p050.html
Name CDC25B Antibody - N-terminal region (AVARP03041_P050)
Protein Size (# AA) 580 amino acids
Molecular Weight 65kDa
NCBI Gene Id 994
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Cell division cycle 25 homolog B (S. pombe)
Peptide Sequence Synthetic peptide located within the following region: MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Uchida,S., et al., (2004) Biochem. Biophys. Res. Commun. 316 (1), 226-232
Description of Target CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined.
Protein Interactions BTRC; UBC; FBXW11; MAPK9; CDK5; CDK1; YWHAQ; MAPKAPK2; UBD; BRSK2; CDC14A; CDK2; Cdc25b; FOXM1; BRSK1; FHL3; KAT2B; MELK; YWHAE; CHEK1; AURKA; SFN; YWHAB; YWHAZ; MAPK14; CREBBP; AR; ESR1; CSNK2B; CSNK2A1; YWHAH; PGR; PHB2; KRT85; KRT35; KRT31;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CDC25B (AVARP03041_P050) antibody
Blocking Peptide For anti-CDC25B (AVARP03041_P050) antibody is Catalog # AAP30149 (Previous Catalog # AAPP00306)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25B
Uniprot ID P30305
Protein Name M-phase inducer phosphatase 2
Sample Type Confirmation

CDC25B is supported by BioGPS gene expression data to be expressed in Daudi

Protein Accession # NP_068659
Purification Affinity Purified
Nucleotide Accession # NM_021873
Tested Species Reactivity Human
Gene Symbol CDC25B
Predicted Species Reactivity Dog, Guinea Pig, Horse, Pig, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Dog: 76%; Guinea Pig: 100%; Horse: 90%; Pig: 92%; Rabbit: 84%
Image 1
Human Daudi
WB Suggested Anti-CDC25B Antibody Titration: 0.2-1 ug/ml
Positive Control: Daudi cell lysateCDC25B is supported by BioGPS gene expression data to be expressed in Daudi
Image 2
Human Liver
Human Liver
 

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