| Product Number |
AVARP03025_P050 |
| Product Page |
www.avivasysbio.com/cdk5-antibody-n-terminal-region-avarp03025-p050.html |
| Name |
CDK5 Antibody - N-terminal region (AVARP03025_P050) |
| Protein Size (# AA) |
292 amino acids |
| Molecular Weight |
33kDa |
| NCBI Gene Id |
1020 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Cyclin-dependent kinase 5 |
| Alias Symbols |
LIS7, PSSALRE |
| Peptide Sequence |
Synthetic peptide located within the following region: SLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Liu,R., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (21), 7570-7575 |
| Description of Target |
CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. The protein can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. And it is also thought to interacts with p35 which activates the kinase. |
| Protein Interactions |
CHFR; CCND2; CDKN1A; EGFR; UBC; DCLK3; CDK5; CCNE1; CDK5R1; CABLES1; CABLES2; STIP1; CDKN1B; CCND3; CCNB1; C2CD5; KIAA0195; FIBP; PPARG; CDK18; HSP90AB1; HSP90AA1; HIST1H1B; GLUD1; CDK3; CDC25B; CCT6A; CCNA2; CCT3; TCP1; CCT5; CDC37; CCT8; CCT2; CCT4; CCT |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CDK5 (AVARP03025_P050) antibody |
| Blocking Peptide |
For anti-CDK5 (AVARP03025_P050) antibody is Catalog # AAP30154 (Previous Catalog # AAPP00311) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CDK5 |
| Uniprot ID |
Q00535 |
| Protein Name |
Cyclin-dependent kinase 5 |
| Sample Type Confirmation |
CDK5 is supported by BioGPS gene expression data to be expressed in 721_B |
| Protein Accession # |
NP_004926 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004935 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CDK5 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Horse, Pig, Sheep, Zebrafish |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Image 1 | Human 721_B
 | WB Suggested Anti-CDK5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysateCDK5 is supported by BioGPS gene expression data to be expressed in 721_B |
|
| Image 2 | Human Colon
 | Rabbit Anti-CDK5 antibody
Catalog Number: AVARP03025
Formalin Fixed Paraffin Embedded Tissue: Human Colon
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec |
|
