| Product Number |
AVARP03008_P050 |
| Product Page |
www.avivasysbio.com/ccng1-antibody-n-terminal-region-avarp03008-p050.html |
| Name |
CCNG1 Antibody - N-terminal region (AVARP03008_P050) |
| Protein Size (# AA) |
295 amino acids |
| Molecular Weight |
34kDa |
| NCBI Gene Id |
900 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Cyclin G1 |
| Alias Symbols |
CCNG |
| Peptide Sequence |
Synthetic peptide located within the following region: IEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Freemantle,S.J., (2007) J. Cell. Biochem. 102 (4), 869-877 |
| Description of Target |
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. CCNG1 is a member of the cyclin family and contains the cyclin box. It lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. |
| Protein Interactions |
KRTAP10-7; SPERT; KRT40; LZTS2; HMBOX1; PAK7; TFIP11; RBPMS; TNIP1; PNMA1; SHKBP1; PLEKHA4; TFAP2C; NFATC4; LTBP3; GRN; APP; UBC; CDK2; TP73; TP53; PPP2CA; GAK; PPP2R4; CDKN2A; COX2; MDM2; CDK5; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CCNG1 (AVARP03008_P050) antibody |
| Blocking Peptide |
For anti-CCNG1 (AVARP03008_P050) antibody is Catalog # AAP30169 (Previous Catalog # AAPS08901) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG1 |
| Uniprot ID |
P51959 |
| Protein Name |
Cyclin-G1 |
| Protein Accession # |
NP_004051 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004060 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CCNG1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 92%; Human: 100%; Mouse: 92%; Pig: 92%; Rat: 92% |
| Image 1 | Human MCF-7
 | WB Suggested Anti-CCNG1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate |
|
| Image 2 | Human heart
 | Rabbit Anti-CCNG1 Antibody
Catalog Number: AVARP03008_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Nucleus
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
