CDK2 Antibody - C-terminal region (AVARP03006_T100)

Data Sheet
 
Product Number AVARP03006_T100
Product Page www.avivasysbio.com/cdk2-antibody-c-terminal-region-avarp03006-t100.html
Name CDK2 Antibody - C-terminal region (AVARP03006_T100)
Protein Size (# AA) 298 amino acids
Molecular Weight 34 kDa
NCBI Gene Id 1017
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Cyclin-dependent kinase 2
Alias Symbols CDKN2, p33(CDK2)
Peptide Sequence Synthetic peptide located within the following region: SKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Elledge, S.J., Spottswood, M.R. (1991). EMBO J. 10:2653-2659.
Description of Target Cdk2 is probably involved in the control of the cell cycle. It interacts with cyclins A, D, or E. Activity of cdk2 is maximal during S phase and G2.
Protein Interactions MAPT; CDKN1A; CCNA2; VCP; SAMHD1; IMPDH2; CDK2; SKP1; FZR1; CKS2; CKS1B; CCNE2; GOLGA2; CREBBP; CDKN1C; CDKN1B; CCNE1; CDK13; SKP2; RBL2; RBL1; CCNB1; COPS5; PTMA; HIST1H1A; PRDX1; CCNJ; CDK7; CDK3; EP300; ATP1A1; MYBL2; MNAT1; HSPD1; HSP90AB1; HSP90AA1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CDK2 (AVARP03006_T100) antibody
Blocking Peptide For anti-CDK2 (AVARP03006_T100) antibody is Catalog # AAP30137 (Previous Catalog # AAPP00208)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CDK2
Uniprot ID P24941
Protein Name Cyclin-dependent kinase 2
Sample Type Confirmation

CDK2 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_001789
Purification Protein A purified
Nucleotide Accession # NM_001798
Tested Species Reactivity Human
Gene Symbol CDK2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Goat, Guinea Pig, Rabbit, Sheep, Zebrafish
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Cow: 100%; Goat: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 75%
Image 1

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The peptide sequence is present in a 30 kDa isoform. The protein may be modified by phosphorylation.
 

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