TNFRSF18 Antibody - C-terminal region (AVARP02052_P050)

Data Sheet
 
Product Number AVARP02052_P050
Product Page www.avivasysbio.com/tnfrsf18-antibody-c-terminal-region-avarp02052-p050.html
Name TNFRSF18 Antibody - C-terminal region (AVARP02052_P050)
Protein Size (# AA) 241 amino acids
Molecular Weight 26 kDa
NCBI Gene Id 8784
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Tumor necrosis factor receptor superfamily, member 18
Alias Symbols AITR, GITR, CD357, GITR-D, ENERGEN
Peptide Sequence Synthetic peptide located within the following region: LRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Clark,H.F., et al., (2003) Genome Res. 13 (10), 2265-2270
Description of Target The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Protein Interactions LNX1; TRAF3; TRAF2; TRAF1; TNFSF18; TNFRSF18;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Datasheets/Manuals Printable datasheet for anti-TNFRSF18 (AVARP02052_P050) antibody
Blocking Peptide For anti-TNFRSF18 (AVARP02052_P050) antibody is Catalog # AAP30626 (Previous Catalog # AAPP01279)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18
Uniprot ID Q9Y5U5
Protein Name Tumor necrosis factor receptor superfamily member 18
Protein Accession # NP_004186
Purification Affinity Purified
Nucleotide Accession # NM_004195
Tested Species Reactivity Human
Gene Symbol TNFRSF18
Predicted Species Reactivity Human
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Human: 100%
Image 1
Human Brain
Human Brain
Image 2
Western Blot
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.
 

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