Product Number |
AVARP02052_P050 |
Product Page |
www.avivasysbio.com/tnfrsf18-antibody-c-terminal-region-avarp02052-p050.html |
Name |
TNFRSF18 Antibody - C-terminal region (AVARP02052_P050) |
Protein Size (# AA) |
241 amino acids |
Molecular Weight |
26 kDa |
NCBI Gene Id |
8784 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Tumor necrosis factor receptor superfamily, member 18 |
Alias Symbols |
AITR, GITR, CD357, GITR-D, ENERGEN |
Peptide Sequence |
Synthetic peptide located within the following region: LRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Clark,H.F., et al., (2003) Genome Res. 13 (10), 2265-2270 |
Description of Target |
The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. |
Protein Interactions |
LNX1; TRAF3; TRAF2; TRAF1; TNFSF18; TNFRSF18; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-TNFRSF18 (AVARP02052_P050) antibody |
Blocking Peptide |
For anti-TNFRSF18 (AVARP02052_P050) antibody is Catalog # AAP30626 (Previous Catalog # AAPP01279) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18 |
Uniprot ID |
Q9Y5U5 |
Protein Name |
Tumor necrosis factor receptor superfamily member 18 |
Protein Accession # |
NP_004186 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_004195 |
Tested Species Reactivity |
Human |
Gene Symbol |
TNFRSF18 |
Predicted Species Reactivity |
Human |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Human: 100% |
Image 1 | Human Brain
| Human Brain |
| Image 2 | Western Blot
| 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. |
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