| Product Number |
AVARP01026_P050 |
| Product Page |
www.avivasysbio.com/creb1-antibody-n-terminal-region-avarp01026-p050.html |
| Name |
CREB1 Antibody - N-terminal region (AVARP01026_P050) |
| Protein Size (# AA) |
341 amino acids |
| Molecular Weight |
37kDa |
| NCBI Gene Id |
1385 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
CAMP responsive element binding protein 1 |
| Alias Symbols |
CREB, CREB-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: DSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Mamdani,F., Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (4), 500-504 |
| Description of Target |
CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. |
| Protein Interactions |
UBC; NCOR1; CREM; CREBBP; RPS6KA1; NR5A2; EP300; DEAF1; TP53; CREB1; PRKG1; YAP1; MAPK14; MEIS1; DAXX; TSSK4; AKT1; ATR; SIRT1; SRA1; DR1; ATF7; GSK3B; GSK3A; ATXN3; DNMT3B; RPS6KA5; YY1; RGS13; JUN; HDAC2; HDAC1; CCDC6; PPP1CA; SUMO1; TAF4; POU2F1; MYOD1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CREB1 (AVARP01026_P050) antibody |
| Blocking Peptide |
For anti-CREB1 (AVARP01026_P050) antibody is Catalog # AAP30415 (Previous Catalog # AAPP00938) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CREB1 |
| Uniprot ID |
P16220 |
| Protein Name |
Cyclic AMP-responsive element-binding protein 1 |
| Protein Accession # |
NP_604391 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_134442 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CREB1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Brain
 | WB Suggested Anti-CREB1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human brain |
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