Product Number |
AVARP01005_P050-FITC |
Product Page |
www.avivasysbio.com/bcl2-antibody-n-terminal-region-fitc-avarp01005-p050-fitc.html |
Name |
BCL2 Antibody - N-terminal region : FITC (AVARP01005_P050-FITC) |
Protein Size (# AA) |
239 amino acids |
Molecular Weight |
26kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
596 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
B-cell CLL/lymphoma 2 |
Alias Symbols |
Bcl-2, PPP1R50 |
Peptide Sequence |
Synthetic peptide located within the following region: GHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Reference |
Chen,R., et al., (2004) J. Cell Biol. 166 (2), 193-203 |
Description of Target |
The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. |
Protein Interactions |
KEAP1; SQSTM1; BECN1; UBC; TP53BP2; BID; BCL2L1; BCL2; BAX; BAD; ATP2A3; NR4A1; KRAS; PPID; MDM4; BNIP3; BFAR; CDK1; BAG3; RAF1; IKBKG; TP53; PPP3CC; FKBP8; MAPK8; IKBKB; HSP90AA1; HIF1A; CRYAB; CHUK; PML; BRCA1; AMBRA1; ATG12; BIK; CISD2; MEX3D; PPP1CC; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-BCL2 (AVARP01005_P050-FITC) antibody |
Blocking Peptide |
For anti-BCL2 (AVARP01005_P050-FITC) antibody is Catalog # AAP30327 (Previous Catalog # AAPP00708) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human BCL2 |
Uniprot ID |
P10415 |
Protein Name |
Apoptosis regulator Bcl-2 |
Protein Accession # |
NP_000624 |
Nucleotide Accession # |
NM_000633 |
Gene Symbol |
BCL2 |
Predicted Species Reactivity |
Human |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Human: 100% |
Image 1 | |
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