| Product Number |
AVARP00032_P050 |
| Product Page |
www.avivasysbio.com/tnfrsf10b-antibody-n-terminal-region-avarp00032-p050.html |
| Name |
TNFRSF10B Antibody - N-terminal region (AVARP00032_P050) |
| Protein Size (# AA) |
440 amino acids |
| Molecular Weight |
42kDa |
| NCBI Gene Id |
8795 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Tumor necrosis factor receptor superfamily, member 10b |
| Alias Symbols |
DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5 |
| Peptide Sequence |
Synthetic peptide located within the following region: LVLVVAAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHI |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Baritaki,S., (2008) J. Immunol. 180 (9), 6199-6210 |
| Description of Target |
The protein is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. |
| Protein Interactions |
TNFSF10; UBC; CFLAR; FADD; CUL3; TRAF2; CASP8; TNFRSF10A; RIPK1; TNFAIP3; ITCH; CBL; TNFRSF10D; MADD; TRADD; CASP10; TIMM50; EZR; TNFRSF1A; MAPK8; MSN; BID; ARHGDIA; RHOA; FASLG; FAS; TP53; RARA; PRKCD; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TNFRSF10B (AVARP00032_P050) antibody |
| Blocking Peptide |
For anti-TNFRSF10B (AVARP00032_P050) antibody is Catalog # AAP30519 (Previous Catalog # AAPP01155) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF10B |
| Uniprot ID |
O14763 |
| Protein Name |
Tumor necrosis factor receptor superfamily member 10B |
| Sample Type Confirmation |
TNFRSF10B is strongly supported by BioGPS gene expression data to be expressed in 721_B |
| Protein Accession # |
NP_003833 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003842 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TNFRSF10B |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human 721_B
 | WB Suggested Anti-TNFRSF10B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysateTNFRSF10B is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells |
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