CFLAR Antibody - N-terminal region (AVARP00022_T100)

Data Sheet
 
Product Number AVARP00022_T100
Product Page www.avivasysbio.com/cflar-antibody-n-terminal-region-avarp00022-t100.html
Name CFLAR Antibody - N-terminal region (AVARP00022_T100)
Protein Size (# AA) 480 amino acids
Molecular Weight 55kDa
NCBI Gene Id 8837
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name CASP8 and FADD-like apoptosis regulator
Alias Symbols CASH, FLIP, MRIT, CLARP, FLAME, cFLIP, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1
Peptide Sequence Synthetic peptide located within the following region: HQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Kondo,G., et al., (2005) Oncol Rep. 14(5), 1215-22
Description of Target CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.
Protein Interactions FADD; TRAF1; GSN; SPATS1; TNFSF10; RIPK1; RAF1; SMAD3; CASP8; HSP90AA1; STUB1; TNFRSF10A; TNFRSF10B; UBC; FASLG; ITCH; DAXX; CBLB; ATG3; XRCC6; Mib1; TP53; DEDD2; DEDD; RIPK2; IKBKB; MAP2K7; TRAF2; CASP10; CASP7; CASP6; MAP2K4; PSEN2; CASP2; CASP3; BCL2L1
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CFLAR (AVARP00022_T100) antibody
Blocking Peptide For anti-CFLAR (AVARP00022_T100) antibody is Catalog # AAP30495 (Previous Catalog # AAPP01131)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CFLAR
Uniprot ID O15519
Protein Name CASP8 and FADD-like apoptosis regulator
Sample Type Confirmation

CFLAR is strongly supported by BioGPS gene expression data to be expressed in HepG2

Protein Accession # NP_003870
Purification Protein A purified
Nucleotide Accession # NM_003879
Tested Species Reactivity Human
Gene Symbol CFLAR
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Horse
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 86%; Horse: 93%; Human: 100%; Mouse: 80%; Rat: 80%
Image 1
Human 293T
Lanes:
Lane 1: 10ug hFLIPL transfected 293 lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit HRP
Secondary Antibody Dilution:
1:2000
Gene Name:
CFLAR
Submitted by:
Dr. Tencho Tenev, The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research
Image 2
Human HepG2
Host: Rabbit
Target Name: CFLAR
Sample Tissue: Human HepG2
Antibody Dilution: 1.0ug/ml
 

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