| Product Number |
AVARP00006_P050 |
| Product Page |
www.avivasysbio.com/adrb2-antibody-middle-region-avarp00006-p050.html |
| Name |
ADRB2 Antibody - middle region (AVARP00006_P050) |
| Protein Size (# AA) |
413 amino acids |
| Molecular Weight |
46kDa |
| NCBI Gene Id |
154 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Adrenergic, beta-2-, receptor, surface |
| Alias Symbols |
BAR, B2AR, ADRBR, ADRB2R, BETA2AR |
| Peptide Sequence |
Synthetic peptide located within the following region: TGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Penco,S., (er) BMC Bioinformatics 9 (1), 254 (2008) In press |
| Description of Target |
This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
ARRDC3; REL; TSHR; TSG101; STAT4; STAT3; SNCG; RGS10; RGS2; RAN; RAB27A; RAB3A; CNN1; CD81; CD68; CD9; CD4; CCKBR; CEACAM1; ARRB2; ARHGDIA; ARHGAP5; HDAC6; GPR56; VAPA; RGS9; RGS11; RGS20; RGS5; VEGFB; VDAC2; VDAC1; KCTD13; ARRDC1; RGS8; SLC52A2; WNK1; RA |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ADRB2 (AVARP00006_P050) antibody |
| Blocking Peptide |
For anti-ADRB2 (AVARP00006_P050) antibody is Catalog # AAP30422 (Previous Catalog # AAPP01005) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human ADRB2 |
| Uniprot ID |
P07550 |
| Protein Name |
Beta-2 adrenergic receptor |
| Protein Accession # |
NP_000015 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000024 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ADRB2 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human OVCAR-3
 | WB Suggested Anti-ADRB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: OVCAR-3 cell lysate |
|
| Image 2 | Hum. Fetal Lung
 | Hum. Fetal Lung |
|
| Image 3 | Human Fetal Lung
 | Host: Rabbit
Target Name: ADRB2
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml |
|
