USH1C Antibody - C-terminal region (ARP96739_P050)

Data Sheet
 
Product Number ARP96739_P050
Product Page www.avivasysbio.com/ush1c-antibody-c-terminal-region-arp96739-p050.html
Name USH1C Antibody - C-terminal region (ARP96739_P050)
Protein Size (# AA) 403 amino acids
Molecular Weight 46 kDa
NCBI Gene Id 10083
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Usher syndrome 1C
Alias Symbols PDZ73, AIE-75, DFNB18, PDZ-45, PDZ-73, PDZD7C, DFNB18A, NY-CO-37, NY-CO-38, ush1cpst, PDZ-73/NY-CO-38
Peptide Sequence Synthetic peptide located within the following region: QRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEQ
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips.
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-USH1C (ARP96739_P050) antibody
Blocking Peptide For anti-USH1C (ARP96739_P050) antibody is Catalog # AAP96739
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human USH1C
Uniprot ID Q9Y6N9-3
Protein Name harmonin
Protein Accession # NP_001284693.1
Purification Affinity purified
Nucleotide Accession # NM_001297764.1
Tested Species Reactivity Human
Gene Symbol USH1C
Predicted Species Reactivity Human
Application WB
Image 1
Human HepG2 Whole Cell
Host: Rabbit
Target Name: USH1C
Sample Tissue: Human HepG2 Whole Cell lysates
Antibody Dilution: 1ug/ml
 

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