Product Number |
ARP96739_P050 |
Product Page |
www.avivasysbio.com/ush1c-antibody-c-terminal-region-arp96739-p050.html |
Name |
USH1C Antibody - C-terminal region (ARP96739_P050) |
Protein Size (# AA) |
403 amino acids |
Molecular Weight |
46 kDa |
NCBI Gene Id |
10083 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Usher syndrome 1C |
Alias Symbols |
PDZ73, AIE-75, DFNB18, PDZ-45, PDZ-73, PDZD7C, DFNB18A, NY-CO-37, NY-CO-38, ush1cpst, PDZ-73/NY-CO-38 |
Peptide Sequence |
Synthetic peptide located within the following region: QRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEQ |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips. |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-USH1C (ARP96739_P050) antibody |
Blocking Peptide |
For anti-USH1C (ARP96739_P050) antibody is Catalog # AAP96739 |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human USH1C |
Uniprot ID |
Q9Y6N9-3 |
Protein Name |
harmonin |
Protein Accession # |
NP_001284693.1 |
Purification |
Affinity purified |
Nucleotide Accession # |
NM_001297764.1 |
Tested Species Reactivity |
Human |
Gene Symbol |
USH1C |
Predicted Species Reactivity |
Human |
Application |
WB |
Image 1 | Human HepG2 Whole Cell
| Host: Rabbit Target Name: USH1C Sample Tissue: Human HepG2 Whole Cell lysates Antibody Dilution: 1ug/ml |
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