Product Number |
ARP88148_P050 |
Product Page |
www.avivasysbio.com/pabpn1-antibody-middle-region-arp88148-p050.html |
Name |
PABPN1 Antibody - middle region (ARP88148_P050) |
Protein Size (# AA) |
296 amino acids |
Molecular Weight |
31 kDa |
NCBI Gene Id |
8106 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
poly(A) binding protein, nuclear 1 |
Alias Symbols |
OPMD, PAB2, PABII, PABP2, PABP-2 |
Peptide Sequence |
Synthetic peptide located within the following region: LLLEPEPEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEGDP |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-PABPN1 (ARP88148_P050) antibody |
Blocking Peptide |
For anti-PABPN1 (ARP88148_P050) antibody is Catalog # AAP88148 |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human PABPN1 |
Uniprot ID |
Q86U42-2 |
Protein Name |
polyadenylate-binding protein 2 |
Protein Accession # |
NP_004634.1 |
Purification |
Affinity purified |
Nucleotide Accession # |
NM_004643.3 |
Tested Species Reactivity |
Human |
Gene Symbol |
PABPN1 |
Predicted Species Reactivity |
Human |
Application |
WB |
Image 1 | Human DLD1 Whole Cell
| Host: Rabbit Target Name: PABPN1 Sample Tissue: Human DLD1 Whole Cell lysates Antibody Dilution: 1ug/ml |
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