PABPN1 Antibody - middle region (ARP88148_P050)

Data Sheet
 
Product Number ARP88148_P050
Product Page www.avivasysbio.com/pabpn1-antibody-middle-region-arp88148-p050.html
Name PABPN1 Antibody - middle region (ARP88148_P050)
Protein Size (# AA) 296 amino acids
Molecular Weight 31 kDa
NCBI Gene Id 8106
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name poly(A) binding protein, nuclear 1
Alias Symbols OPMD, PAB2, PABII, PABP2, PABP-2
Peptide Sequence Synthetic peptide located within the following region: LLLEPEPEPEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEGDP
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-PABPN1 (ARP88148_P050) antibody
Blocking Peptide For anti-PABPN1 (ARP88148_P050) antibody is Catalog # AAP88148
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PABPN1
Uniprot ID Q86U42-2
Protein Name polyadenylate-binding protein 2
Protein Accession # NP_004634.1
Purification Affinity purified
Nucleotide Accession # NM_004643.3
Tested Species Reactivity Human
Gene Symbol PABPN1
Predicted Species Reactivity Human
Application WB
Image 1
Human DLD1 Whole Cell
Host: Rabbit
Target Name: PABPN1
Sample Tissue: Human DLD1 Whole Cell lysates
Antibody Dilution: 1ug/ml
 

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