Product Number |
ARP84780_P050 |
Product Page |
www.avivasysbio.com/eya4-antibody-middle-region-arp84780-p050.html |
Name |
EYA4 Antibody - middle region (ARP84780_P050) |
Protein Size (# AA) |
639 amino acids |
Molecular Weight |
70 kDa |
NCBI Gene Id |
2070 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
EYA transcriptional coactivator and phosphatase 4 |
Alias Symbols |
CMD1J, DFNA10 |
Peptide Sequence |
Synthetic peptide located within the following region: IKDLDERTCRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDLDETIIVFHS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-EYA4 (ARP84780_P050) antibody |
Blocking Peptide |
For anti-EYA4 (ARP84780_P050) antibody is Catalog # AAP84780 |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human EYA4 |
Uniprot ID |
O95677 |
Protein Name |
eyes absent homolog 4 |
Protein Accession # |
NP_001287941.1 |
Purification |
Affinity purified |
Nucleotide Accession # |
NM_001301012.1 |
Tested Species Reactivity |
Human |
Gene Symbol |
EYA4 |
Predicted Species Reactivity |
Human |
Application |
WB |
Image 1 | Human Hela Whole Cell
| Host: Rabbit Target Name: EYA4 Sample Tissue: Human Hela Whole Cell lysates Antibody Dilution: 1ug/ml |
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