Product Number |
ARP75860_P050-FITC |
Product Page |
www.avivasysbio.com/march8-antibody-n-terminal-region-fitc-arp75860-p050-fitc.html |
Name |
MARCH8 Antibody - N-terminal region : FITC (ARP75860_P050-FITC) |
Protein Size (# AA) |
291 amino acids |
Molecular Weight |
32kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
220972 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
membrane associated ring-CH-type finger 8 |
Alias Symbols |
MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII |
Peptide Sequence |
Synthetic peptide located within the following region: MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Reference |
N/A |
Description of Target |
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010] |
Protein Interactions |
TNFRSF10A; UBC; UBE2H; UBE2D1; TFRC; UBE2D3; IL1RAP; IL1R1; CD86; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-MARCH8 (ARP75860_P050-FITC) antibody |
Blocking Peptide |
For anti-MARCH8 (ARP75860_P050-FITC) antibody is Catalog # AAP75860 |
Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MARH8 |
Uniprot ID |
Q5T0T0 |
Protein Name |
E3 ubiquitin-protein ligase MARCH8 |
Purification |
Affinity purified |
Gene Symbol |
MARCH8 |
Predicted Species Reactivity |
Human |
Application |
WB |
Image 1 | |
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