| Product Number |
ARP75560_P050-FITC |
| Product Page |
www.avivasysbio.com/ubxn1-antibody-n-terminal-region-fitc-arp75560-p050-fitc.html |
| Name |
UBXN1 Antibody - N-terminal region : FITC (ARP75560_P050-FITC) |
| Protein Size (# AA) |
297 amino acids |
| Molecular Weight |
32kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
51035 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
2B28, SAKS1, UBXD10 |
| Peptide Sequence |
Synthetic peptide located within the following region: GRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPTSS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
N/A |
| Description of Target |
UBXN1 is a ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. It specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1,it leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. It is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. |
| Protein Interactions |
UBXN1; UBQLN1; FAM189A2; PLAA; TRIM39; VCP; UBE2I; UBC; PLA2G4A; MAVS; NSFL1C; STK26; TRNT1; MCTS1; TWF2; PROSC; BASP1; DENR; YWHAE; TXNRD1; TUFM; TUBB2A; PAFAH1B1; HSPA5; HMGB3; HK1; CTPS1; CAPN2; CD81; CSE1L; CLNS1A; ATP6V1A; SSSCA1; USP34; SEC22B; VPS4 |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-UBXN1 (ARP75560_P050-FITC) antibody |
| Blocking Peptide |
For anti-UBXN1 (ARP75560_P050-FITC) antibody is Catalog # AAP75560 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBXN1 |
| Uniprot ID |
Q04323 |
| Purification |
Affinity purified |
| Gene Symbol |
UBXN1 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
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