| Product Number |
ARP74556_P050-FITC |
| Product Page |
www.avivasysbio.com/hdac3-antibody-c-terminal-region-fitc-arp74556-p050-fitc.html |
| Name |
HDAC3 Antibody - C-terminal region : FITC (ARP74556_P050-FITC) |
| Protein Size (# AA) |
428 amino acids |
| Molecular Weight |
47kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
8841 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
HD3, RPD3, KDAC3, RPD3-2 |
| Peptide Sequence |
Synthetic peptide located within the following region: DVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Description of Target |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
| Protein Interactions |
PPARG; NFE2L2; CSNK2A1; SAP30; MEF2A; SMAD7; HIF1A; NCOR2; PRDM6; GPS2; ZBTB16; SUMO1; RREB1; TCP1; TBL1X; SOX2; HDAC7; ANKRD11; APPL1; ANKRD12; RCOR1; KDM1A; CCT5; NCOR1; HDAC3; CCT3; TBL1XR1; RCOR3; CCT8; CCT2; CCT4; CCT7; CCT6A; TRIM28; STAT3; vif; ZBT |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-HDAC3 (ARP74556_P050-FITC) antibody |
| Blocking Peptide |
For anti-HDAC3 (ARP74556_P050-FITC) antibody is Catalog # AAP74556 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human HDAC3 |
| Uniprot ID |
O15379 |
| Protein Accession # |
NP_003874 |
| Purification |
Affinity Purified |
| Gene Symbol |
HDAC3 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
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