| Product Number |
ARP74313_P050-FITC |
| Product Page |
www.avivasysbio.com/tsg101-antibody-middle-region-fitc-arp74313-p050-fitc.html |
| Name |
TSG101 Antibody - middle region : FITC (ARP74313_P050-FITC) |
| Protein Size (# AA) |
285 amino acids |
| Molecular Weight |
31kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
7251 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
tumor susceptibility 101 |
| Alias Symbols |
TSG10, VPS23 |
| Peptide Sequence |
Synthetic peptide located within the following region: TGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
N/A |
| Description of Target |
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. |
| Protein Interactions |
USHBP1; CEP55; VPS37C; VPS28; AATF; MGRN1; PDLIM7; TAX1BP1; KRT31; KRT13; KIFC3; DAPK3; AR; FAM9B; VPS37A; HAUS1; SYCE1; UBC; LRSAM1; ADRB2; MVB12A; UBAP1; CDKN1A; HGS; gag; gag-pol; GRB2; CDS2; ZFYVE9; VCP; VPS37B; WDR12; XPO1; UBD; ARRDC1; KCNN4; RAB11F |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-TSG101 (ARP74313_P050-FITC) antibody |
| Blocking Peptide |
For anti-TSG101 (ARP74313_P050-FITC) antibody is Catalog # AAP74313 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human TS101 |
| Uniprot ID |
Q99816-2 |
| Protein Name |
tumor susceptibility gene 101 protein |
| Purification |
Affinity purified |
| Gene Symbol |
TSG101 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
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