Product Number |
ARP74244_P050-FITC |
Product Page |
www.avivasysbio.com/smurf1-antibody-n-terminal-region-fitc-arp74244-p050-fitc.html |
Name |
SMURF1 Antibody - N-terminal region : FITC (ARP74244_P050-FITC) |
Protein Size (# AA) |
757 amino acids |
Molecular Weight |
83kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
57154 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
SMAD specific E3 ubiquitin protein ligase 1 |
Alias Symbols |
KIAA1625 |
Peptide Sequence |
Synthetic peptide located within the following region: QRLQAQRLRNPDVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLH |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Description of Target |
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Protein Interactions |
UBE2L3; SMURF1; TRIB2; POLR2A; SMAD1; UBC; PTCH1; UBE2M; UBE2D3; NEDD8; SENP8; SMAD7; SMAD4; TRAF4; AXIN1; HCVgp1; EFNB1; FBXL15; FBXO42; RNF11; FBXL5; FBXO21; YWHAQ; SMAD5; SMAD3; SMAD2; BTRC; CCDC88C; HNRNPA3; TUBB; E2F7; CMBL; TIMM50; RBM17; RIOK1; WDR |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-SMURF1 (ARP74244_P050-FITC) antibody |
Blocking Peptide |
For anti-SMURF1 (ARP74244_P050-FITC) antibody is Catalog # AAP74244 |
Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human SMUF1 |
Uniprot ID |
Q9HCE7 |
Protein Name |
E3 ubiquitin-protein ligase SMURF1 |
Purification |
Affinity Purified |
Gene Symbol |
SMURF1 |
Predicted Species Reactivity |
Human |
Application |
WB |
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