Product Number |
ARP74198_P050 |
Product Page |
www.avivasysbio.com/safb-antibody-middle-region-arp74198-p050.html |
Name |
SAFB Antibody - middle region (ARP74198_P050) |
Protein Size (# AA) |
848 amino acids |
Molecular Weight |
93kDa |
NCBI Gene Id |
6294 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
scaffold attachment factor B |
Alias Symbols |
HAP, HET, SAF-B, SAFB1, SAB-B1, SAF-B1 |
Peptide Sequence |
Synthetic peptide located within the following region: TELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKC |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene. |
Protein Interactions |
SUMO3; STAU1; UBC; LGR4; SUMO1; EED; rev; TP63; IL7R; CSNK2A1; MAP1LC3A; TP53BP1; TRMT112; TMOD2; RBMX; NCSTN; ACIN1; SMU1; U2AF2; CPSF6; GCN1L1; UTP14A; USP39; SAP18; VTN; U2AF1; TPBG; SURF4; SON; SRSF7; PRKAR1A; ABCC1; LAMP2; SEPT7; AK2; ACAT1; ZC3H18; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SAFB (ARP74198_P050) antibody |
Blocking Peptide |
For anti-SAFB (ARP74198_P050) antibody is Catalog # AAP74198 |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human SAFB1 |
Uniprot ID |
Q15424-2 |
Protein Name |
scaffold attachment factor B1 |
Purification |
Affinity Purified |
Tested Species Reactivity |
Human |
Gene Symbol |
SAFB |
Predicted Species Reactivity |
Human |
Application |
WB |
Image 1 | Human 786-0 Whole Cell
| Host: Rabbit Target Name: SAFB1 Sample Type: 786-0 Whole Cell lysates Antibody Dilution: 1.0ug/ml |
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