Product Number |
ARP74196_P050-FITC |
Product Page |
www.avivasysbio.com/runx3-antibody-c-terminal-region-fitc-arp74196-p050-fitc.html |
Name |
RUNX3 Antibody - C-terminal region : FITC (ARP74196_P050-FITC) |
Protein Size (# AA) |
415 amino acids |
Molecular Weight |
45kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
864 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Alias Symbols |
AML2, CBFA3, PEBP2aC |
Peptide Sequence |
Synthetic peptide located within the following region: PQNQSGPFQANPSPYHLYYGTSSGSYQFSMVAGSSSGGDRSPTRMLASCT |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Reference |
N/A |
Description of Target |
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
Protein Interactions |
Dlg4; UBC; PML; PIN1; NOTCH1; RBPJ; SIRT2; Cdk4; MDM2; EZH2; Vdr; SMURF2; SMURF1; HDAC9; SUV39H1; SMAD3; EP300; CBFB; SP110; HDAC5; HDAC4; HDAC2; HDAC1; TLE1; SMAD1; YAP1; SMAD5; SMAD2; PHB2; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-RUNX3 (ARP74196_P050-FITC) antibody |
Blocking Peptide |
For anti-RUNX3 (ARP74196_P050-FITC) antibody is Catalog # AAP74196 |
Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human RUNX3 |
Uniprot ID |
Q13761 |
Purification |
Affinity purified |
Gene Symbol |
RUNX3 |
Predicted Species Reactivity |
Human |
Application |
WB |
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