| Product Number |
ARP73820_P050-FITC |
| Product Page |
www.avivasysbio.com/derl1-antibody-c-terminal-region-fitc-arp73820-p050-fitc.html |
| Name |
DERL1 Antibody - C-terminal region : FITC (ARP73820_P050-FITC) |
| Protein Size (# AA) |
251 amino acids |
| Molecular Weight |
27kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
79139 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
DER1, DER-1, derlin-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: STPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Description of Target |
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
| Protein Interactions |
HM13; TCF25; XBP1; EGFR; USP19; ZFAND2B; Vcp; PTGS2; CAV1; SYVN1; DERL2; SHH; SEL1L; SERPINA1; FAF2; ALB; APP; DERL1; EDEM1; RNF5; RHO; NGLY1; BCAP31; CFTR; UBXN6; TRAM1; APOB; CLN6; UBXN4; ERN1; ASGR2; UBE2J1; ERLIN2; UBC; HLA-A; CACNA1C; YOD1; VIMP; KPN |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-DERL1 (ARP73820_P050-FITC) antibody |
| Blocking Peptide |
For anti-DERL1 (ARP73820_P050-FITC) antibody is Catalog # AAP73820 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human DERL1 |
| Uniprot ID |
Q9BUN8 |
| Protein Accession # |
NP_077271 |
| Purification |
Affinity Purified |
| Gene Symbol |
DERL1 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
|
