Product Number |
ARP72581_P050-FITC |
Product Page |
www.avivasysbio.com/sp100-antibody-middle-region-fitc-arp72581-p050-fitc.html |
Name |
SP100 Antibody - middle region : FITC (ARP72581_P050-FITC) |
Protein Size (# AA) |
879 amino acids |
Molecular Weight |
96kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
6672 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Alias Symbols |
lysp100b |
Peptide Sequence |
Synthetic peptide located within the following region: IIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEAT |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Description of Target |
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. |
Protein Interactions |
RBM39; DYRK2; SUMO1; UBE2I; SP100; SUMO2; SUMO3; PHC1; DNMT3A; ACTN2; RTP5; L3MBTL3; TRAF3IP3; GIPC2; AMOTL2; ZC2HC1A; SENP1; CBX5; USPL1; UBC; PML; VPS25; PUS1; CRTAP; TOM1L1; SERPINE2; AGL; CREM; DSTN; AHCYL1; SEC23A; IGBP1; ETS1; ARID3A; TERF2IP; TERF2 |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-SP100 (ARP72581_P050-FITC) antibody |
Blocking Peptide |
For anti-SP100 (ARP72581_P050-FITC) antibody is Catalog # AAP72581 |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human SP100 |
Uniprot ID |
P23497 |
Protein Accession # |
NP_003104 |
Purification |
Affinity Purified |
Gene Symbol |
SP100 |
Predicted Species Reactivity |
Human |
Application |
WB |
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