| Product Number |
ARP72533_P050-FITC |
| Product Page |
www.avivasysbio.com/gss-antibody-c-terminal-region-fitc-arp72533-p050-fitc.html |
| Name |
GSS Antibody - C-terminal region : FITC (ARP72533_P050-FITC) |
| Protein Size (# AA) |
474 amino acids |
| Molecular Weight |
52kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
2937 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
GSHS, HEL-S-64p, HEL-S-88n |
| Peptide Sequence |
Synthetic peptide located within the following region: EEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERAS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Description of Target |
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. |
| Protein Interactions |
GSS; UBC; GINS3; OLA1; DCPS; ABHD14A; RRAGB; PDIA4; USP14; YWHAH; YWHAG; YWHAE; YWHAB; VCL; RAP1GDS1; PPP5C; PAFAH1B2; MVK; MSN; HMGB3; ECHS1; TBCB; ASS1; ASNS; CDK9; TERF1; GSTZ1; |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-GSS (ARP72533_P050-FITC) antibody |
| Blocking Peptide |
For anti-GSS (ARP72533_P050-FITC) antibody is Catalog # AAP72533 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human GSS |
| Uniprot ID |
P48637 |
| Protein Accession # |
XP_005260463 |
| Purification |
Affinity Purified |
| Gene Symbol |
GSS |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86% |
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