| Product Number |
ARP72517_P050-FITC |
| Product Page |
www.avivasysbio.com/casp9-antibody-middle-region-fitc-arp72517-p050-fitc.html |
| Name |
CASP9 Antibody - middle region : FITC (ARP72517_P050-FITC) |
| Protein Size (# AA) |
266 amino acids |
| Molecular Weight |
29kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
842 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6 |
| Peptide Sequence |
Synthetic peptide located within the following region: QKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Description of Target |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. |
| Protein Interactions |
BAX; XIAP; BIRC2; APAF1; BIRC8; BIRC7; ABL1; PTCH1; CRYAB; SQSTM1; JUN; CASP7; CASP3; BRCA1; RB1; MSTO1; HSD17B4; BIRC3; VCP; BIRC6; UBC; RNF2; MZB1; CARD8; GMEB1; NAIP; NLRP1; NOD1; DIABLO; BCL10; BIRC5; ILK; CASP9; MAPK3; HIP1; CASP10; MAP2K2; SRF; BCL2 |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-CASP9 (ARP72517_P050-FITC) antibody |
| Blocking Peptide |
For anti-CASP9 (ARP72517_P050-FITC) antibody is Catalog # AAP72517 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human CASP9 |
| Uniprot ID |
P55211-2 |
| Purification |
Affinity Purified |
| Gene Symbol |
CASP9 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
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