Product Number |
ARP72502_P050-FITC |
Product Page |
www.avivasysbio.com/ercc8-antibody-c-terminal-region-fitc-arp72502-p050-fitc.html |
Name |
ERCC8 Antibody - C-terminal region : FITC (ARP72502_P050-FITC) |
Protein Size (# AA) |
396 amino acids |
Molecular Weight |
43kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
1161 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Alias Symbols |
CSA, CKN1, UVSS2 |
Peptide Sequence |
Synthetic peptide located within the following region: QSNFQELYSGSRDCNILAWVPSLYEPVPDDDETTTKSQLNPAFEDAWSSS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Description of Target |
This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. |
Protein Interactions |
CUL4A; CUL4B; DDB1; RUVBL2; ZNF24; PCNA; H1F0; ERCC6; UVSSA; DDA1; RFWD2; COPS4; COPS6; COPS3; TOP1; TP53; SSBP1; OGG1; MDM2; GTF2H2; CUL5; GPS1; DDB2; COPS2; COPS7A; COPS5; COPS8; RBX1; POLR2A; HMGN1; EP300; UBC; CSNK2B; XAB2; UQCRQ; CBR1; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-ERCC8 (ARP72502_P050-FITC) antibody |
Blocking Peptide |
For anti-ERCC8 (ARP72502_P050-FITC) antibody is Catalog # AAP72502 |
Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ERCC8 |
Uniprot ID |
Q13216 |
Protein Accession # |
NP_000073 |
Purification |
Affinity Purified |
Gene Symbol |
ERCC8 |
Predicted Species Reactivity |
Human |
Application |
WB |
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