| Product Number |
ARP72475_P050 |
| Product Page |
www.avivasysbio.com/rad51-antibody-n-terminal-region-arp72475-p050.html |
| Name |
RAD51 Antibody - N-terminal region (ARP72475_P050) |
| Protein Size (# AA) |
280 amino acids |
| Molecular Weight |
30kDa |
| NCBI Gene Id |
5888 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
RECA, BRCC5, FANCR, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930 |
| Peptide Sequence |
Synthetic peptide located within the following region: VEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Protein Interactions |
BRCA1; ATRX; FBXO18; PALB2; HNRNPC; SWSAP1; HNRNPA2B1; RPA3; RPA1; RAD52; PFN1; RAD54B; AICDA; BLM; DMC1; NXF1; RECQL5; UGDH; CHEK1; BRCA2; SFR1; SWI5; NEDD8; PML; TERF2IP; TP53; MSH2; MSH6; UBC; UHRF2; RAD51AP1; WRN; POLN; MORF4L1; MDC1; RAD51C; MCPH1; S |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RAD51 (ARP72475_P050) antibody |
| Blocking Peptide |
For anti-RAD51 (ARP72475_P050) antibody is Catalog # AAP72475 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human RAD51 |
| Uniprot ID |
Q06609-3 |
| Purification |
Affinity Purified |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RAD51 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | Human HCT15
 | Host: Rabbit
Target Name: RAD51
Sample Type: HCT15 Whole Cell lysates
Antibody Dilution: 1.0ug/ml |
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