PCNA Antibody - N-terminal region : FITC (ARP72403_P050-FITC)

Data Sheet
 
Product Number ARP72403_P050-FITC
Product Page www.avivasysbio.com/pcna-antibody-n-terminal-region-fitc-arp72403-p050-fitc.html
Name PCNA Antibody - N-terminal region : FITC (ARP72403_P050-FITC)
Protein Size (# AA) 261 amino acids
Molecular Weight 28kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 5111
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Alias Symbols ATLD2
Peptide Sequence Synthetic peptide located within the following region: AMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEM
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Protein Interactions GADD45A; CDKN1A; HUWE1; POLH; PCNA; MSH3; FUS; UBC; TMEM218; CHFR; DTL; POLE; POLD1; MCM7; MCM4; LIG1; MSH6; FEN1; FBXO18; ZRANB3; CHTF18; DNMT1; RAD18; SIVA1; KIAA0101; TDG; SUMO2; SUMO3; RPA1; RFC5; RFC4; RFC3; RFC2; RFC1; MDM2; TRIM25; USP18; ISG15; MA
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-PCNA (ARP72403_P050-FITC) antibody
Blocking Peptide For anti-PCNA (ARP72403_P050-FITC) antibody is Catalog # AAP72403
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human PCNA
Uniprot ID P12004
Protein Accession # NP_872590
Purification Affinity Purified
Gene Symbol PCNA
Predicted Species Reactivity Human
Application WB
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