| Product Number |
ARP64428_P050 |
| Product Page |
www.avivasysbio.com/aqr-antibody-c-terminal-region-arp64428-p050.html |
| Name |
AQR Antibody - C-terminal region (ARP64428_P050) |
| Protein Size (# AA) |
1485 amino acids |
| Molecular Weight |
171kDa |
| NCBI Gene Id |
9716 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Aquarius homolog (mouse) |
| Alias Symbols |
IBP160, fSAP164 |
| Peptide Sequence |
Synthetic peptide located within the following region: DTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. |
| Protein Interactions |
UBC; LGR4; SUZ12; RNF2; BMI1; ZNF830; WDR83; WDR77; RBM22; PQBP1; RBM4; EIF4A3; MAGOH; SIRT7; HNRNPA1; Prpf8; Cdc5l; Snw1; USP28; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-AQR (ARP64428_P050) antibody |
| Blocking Peptide |
For anti-AQR (ARP64428_P050) antibody is Catalog # AAP64428 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR |
| Uniprot ID |
O60306 |
| Protein Name |
Intron-binding protein aquarius |
| Sample Type Confirmation |
AQR is supported by BioGPS gene expression data to be expressed in MCF7 |
| Protein Accession # |
NP_055506 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_014691 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
AQR |
| Predicted Species Reactivity |
Human, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Horse: 79%; Human: 100% |
| Image 1 | Human MCF-7
 | WB Suggested Anti-AQR Antibody
Titration: 1.0 ug/ml
Positive Control: MCF7 Whole CellAQR is supported by BioGPS gene expression data to be expressed in MCF7 |
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