| Product Number |
ARP63365_P050 |
| Product Page |
www.avivasysbio.com/mme-antibody-c-terminal-region-arp63365-p050.html |
| Name |
MME Antibody - C-terminal region (ARP63365_P050) |
| Protein Size (# AA) |
750 amino acids |
| Molecular Weight |
83kDa |
| NCBI Gene Id |
4311 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Membrane metallo-endopeptidase |
| Alias Symbols |
NEP, SFE, CD10, CALLA, CMT2T, SCA43 |
| Peptide Sequence |
Synthetic peptide located within the following region: EYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. |
| Protein Interactions |
MME; NPPA; AGT; HDAC8; UBC; NDRG1; FAM83F; RGPD6; POTEI; TUBB8; UBAC2; KBTBD3; MTDH; ITFG3; ARMC10; FAHD1; CDK5RAP3; MRPL44; NUCKS1; MRPS25; LAMTOR1; DNAJB12; SDF4; METTL7A; NNT; CPSF6; PDIA5; RUVBL2; TM9SF1; MRVI1; CLEC4M; ZMPSTE24; RBM39; ATP5J2; SLC9A3 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MME (ARP63365_P050) antibody |
| Blocking Peptide |
For anti-MME (ARP63365_P050) antibody is Catalog # AAP63365 |
| Uniprot ID |
P08473 |
| Protein Name |
Neprilysin |
| Protein Accession # |
NP_009218 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_007287 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
MME |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human OVCAR-3
 | WB Suggested Anti-MME Antibody
Titration: 1.0 ug/ml
Positive Control: OVCAR-3 Whole Cell |
| | Image 2 | Mouse Kidney
 | Host: Mouse
Target Name: MME
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml |
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