| Product Number |
ARP61996_P050 |
| Product Page |
www.avivasysbio.com/bag5-antibody-c-terminal-region-arp61996-p050.html |
| Name |
BAG5 Antibody - C-terminal region (ARP61996_P050) |
| Protein Size (# AA) |
488 amino acids |
| Molecular Weight |
56kDa |
| NCBI Gene Id |
9529 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
BCL2-associated athanogene 5 |
| Alias Symbols |
BAG-5 |
| Peptide Sequence |
Synthetic peptide located within the following region: LEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEEL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. |
| Protein Interactions |
CCDC155; FAM118B; THAP1; BANP; MAD1L1; TP53; TRIM27; FAM96B; MAD2L1; DLG5; UBC; LATS2; SOX2; MMS19; CIRBP; LRRK2; CUL3; FBXO25; PARK2; HSPA4; SNCA; STUB1; OTUD4; UIMC1; BAG5; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-BAG5 (ARP61996_P050) antibody |
| Blocking Peptide |
For anti-BAG5 (ARP61996_P050) antibody is Catalog # AAP61996 (Previous Catalog # AAPP48333) |
| Uniprot ID |
Q9UL15-2 |
| Protein Name |
BAG family molecular chaperone regulator 5 |
| Publications |
A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis. Cell Discov. 2, 16039 (2016). 27807478 |
| Sample Type Confirmation |
BAG5 is supported by BioGPS gene expression data to be expressed in HeLa |
| Protein Accession # |
NP_001015049 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001015049 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
BAG5 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rat: 93% |
| Image 1 | Human Fetal liver
 | WB Suggested Anti-BAG5 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Liver |
|
| Image 2 | Human Hela
 | Host: Rabbit
Target Name: BAG5
Sample Type: Human Hela
Antibody Dilution: 1.0ug/mlBAG5 is supported by BioGPS gene expression data to be expressed in HeLa |
|
| Image 3 | siRUVBL1 transfected human Saos2
 | Sample Type:
Lane 1: 20ug siRUVBL1 transfected human Saos2 cells Lane 2: 20ug untransfected human Saos2 cells Primary Antibody Dilution:
1:1000 Secondary Antibody:
Anti-rabbit-HRP Secondary Antibody Dilution:
1:3000 Color/Signal Descriptions:
BAG5 Gene Name:
Wenwei Hu, Xuetian Yue, Rutgers Cancer Institute of New Jersey. Submitted by:
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