UBE2V1 Antibody - C-terminal region (ARP61716_P050)

Data Sheet
 
Product Number ARP61716_P050
Product Page www.avivasysbio.com/ube2v1-antibody-c-terminal-region-arp61716-p050.html
Name UBE2V1 Antibody - C-terminal region (ARP61716_P050)
Protein Size (# AA) 147 amino acids
Molecular Weight 16kDa
NCBI Gene Id 7335
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Ubiquitin-conjugating enzyme E2 variant 1
Alias Symbols CIR1, UEV1, CROC1, UBE2V, UEV-1, UEV1A, CROC-1
Peptide Sequence Synthetic peptide located within the following region: GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Protein Interactions UBC; TRAF6; ube2nb; UBQLN1; FAM168A; TRAF3IP2; STUB1; PARK2; TXNDC5; YWHAQ; ECHS1; YWHAZ; YWHAG; TGM2; LDHB; SFN; G6PD; IQCB1; PELI3; ULK4; POMP; UBXN7; UBE2C; AHCYL1; SSSCA1; UBE4B; TTC9C; ATP6V1G1; ATP6V1F; ZYX; UGDH; UCHL3; UBE2V2; UBE2N; UBE2D2; UBE2B
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-UBE2V1 (ARP61716_P050) antibody
Blocking Peptide For anti-UBE2V1 (ARP61716_P050) antibody is Catalog # AAP61716 (Previous Catalog # AAPP48229)
Uniprot ID Q13404
Protein Name Ubiquitin-conjugating enzyme E2 variant 1
Protein Accession # NP_001027459
Purification Affinity Purified
Nucleotide Accession # NM_001032288
Tested Species Reactivity Human
Gene Symbol UBE2V1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Image 1
Human Fetal Brain
WB Suggested Anti-UBE2V1 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Brain
Image 2

25 ug of the indicated Human whole cell extracts was loaded onto a 10-20% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
 

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