| Product Number |
ARP61404_P050 |
| Product Page |
www.avivasysbio.com/magi2-antibody-n-terminal-region-arp61404-p050.html |
| Name |
MAGI2 Antibody - N-terminal region (ARP61404_P050) |
| Protein Size (# AA) |
1455 amino acids |
| Molecular Weight |
160kDa |
| NCBI Gene Id |
9863 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| Description |
|
| Alias Symbols |
AIP1, AIP-1, ARIP1, SSCAM, MAGI-2, NPHS15, ACVRIP1 |
| Peptide Sequence |
Synthetic peptide located within the following region: EEEEEERPVVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. |
| Protein Interactions |
BAI1; ARRDC3; CTNNB1; ADRB1; DSCAML1; PLXNB3; RAPGEF2; MAGI2; CTNND2; TGFA; GRID2; ATN1; DLL1; SMAD3; PTEN; ACVR2A; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for ARP61404_P050 |
| Blocking Peptide |
Catalog # AAP61404 (Previous Catalog # AAPP47522) |
| Uniprot ID |
Q86UL8 |
| Protein Name |
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 |
| Publications |
Corticosteroid treatment exacerbates nephrotic syndrome in a zebrafish model of magi2a knockout. Kidney Int. 95, 1079-1090 (2019). 31010479
Doukhanine, E., Gavino, C., Haines, J. D., Almazan, G. & Richard, S. The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation. Mol. Biol. Cell 21, 3029-40 (2010). 20631256 |
| Sample Type Confirmation |
MAGI2 is strongly supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_036433 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_012301 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MAGI2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86% |
| Image 1 | Human HEK293T
 | WB Suggested Anti-MAGI2 Antibody
Titration: 1.0 ug/ml
Positive Control: 293T Whole CellMAGI2 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells |
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