Product Number |
ARP61393_P050-FITC |
Product Page |
www.avivasysbio.com/wwox-antibody-n-terminal-region-fitc-arp61393-p050-fitc.html |
Name |
WWOX Antibody - N-terminal region : FITC (ARP61393_P050-FITC) |
Protein Size (# AA) |
363 amino acids |
Molecular Weight |
39kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
51741 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Alias Symbols |
FOR, WOX1, DEE28, EIEE28, FRA16D, SCAR12, HHCMA56, PRO0128, SDR41C1, D16S432E |
Peptide Sequence |
Synthetic peptide located within the following region: EKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPR |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Description of Target |
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. |
Protein Interactions |
ITCH; TRIM28; HUWE1; UBC; ATM; RPRD2; CYFIP1; SPG20; SNRNP200; ACIN1; SLC4A1AP; DHX30; SCAF8; XRN2; GABARAPL2; SEC23IP; HNRNPUL1; DIDO1; CPSF6; SF3B2; SF3A3; SRSF10; USP39; IGF2BP2; IGF2BP3; IGF2BP1; PAICS; PRPF8; CCT2; CCT7; NOP56; DDX17; SEC23A; BAIAP2; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-WWOX (ARP61393_P050-FITC) antibody |
Blocking Peptide |
For anti-WWOX (ARP61393_P050-FITC) antibody is Catalog # AAP61393 |
Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human WWOX |
Uniprot ID |
Q9NZC7-2 |
Purification |
Affinity Purified |
Gene Symbol |
WWOX |
Predicted Species Reactivity |
Human |
Application |
WB |
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