| Product Number |
ARP61353_P050 |
| Product Page |
www.avivasysbio.com/h2afz-antibody-c-terminal-region-arp61353-p050.html |
| Name |
H2AFZ Antibody - C-terminal region (ARP61353_P050) |
| Protein Size (# AA) |
128 amino acids |
| Molecular Weight |
14kDa |
| NCBI Gene Id |
3015 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
H2A histone family, member Z |
| Alias Symbols |
H2AZ, H2A.z, H2A/z, H2AFZ, H2A.Z-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: VKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. |
| Protein Interactions |
UBC; ASB9; ASB16; WWOX; ZBTB1; OGFOD1; TRNT1; ACAA2; NOL3; EZR; PYGL; PSMD9; FH; UBD; PAN2; HIST1H3B; CENPA; MAGEC1; SUMO1; SUMO3; NEDD8; EPC1; MEAF6; ACTR6; EP400; DMAP1; MRGBP; ING3; MORF4L1; RUVBL2; SRCAP; KAT5; RUVBL1; TRRAP; YEATS4; VPS72; ACTL6A; HI |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for ARP61353_P050 |
| Blocking Peptide |
Catalog # AAP61353 (Previous Catalog # AAPP47475) |
| Uniprot ID |
P0C0S5 |
| Protein Name |
Histone H2A.Z |
| Protein Accession # |
NP_002097 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002106 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
H2AFZ |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Image 1 | Human HeLa
 | WB Suggested Anti-H2AFZ Antibody
Titration: 1.0 ug/ml
Positive Control: Hela Whole Cell |
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