ACTA1 Antibody - N-terminal region (ARP60969_P050)

• Product Number: ARP60969_P050
• Name: ACTA1 Antibody - N-terminal region (ARP60969_P050)
• Protein Size (# AA): 377 amino acids
• Molecular Weight: 42kDa
• NCBI Gene Id: 58
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Actin, alpha 1, skeletal muscle
• Alias Symbols: ACTA, ASMA, CFTD, MPFD, NEM1, NEM2, NEM3, SHPM, CFTD1, CFTDM
• Peptide Sequence: Synthetic peptide located within the following region: GQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVA
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
• Protein Interactions: ABL1; TRIM63; TRIM55; CEP57; AMOT; UBC; SUMO3; CDKN2A; ACTG1; BRK1; ACTBL2; NCKAP1; LRCH3; MAPK14; DSTN; NMI; UBL4A; ABRA; ABLIM2; POLR1B; RRN3; HTRA2; PTPN22; ABLIM3; BTK; CCT2; TRAF3IP1; TCP1; SNCA; PARK2; LGALS3; SHC1; GSN; CDK2; CUL1; ISG15; YWHAZ; RE
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-ACTA1 (ARP60969_P050) antibody is Catalog # AAP60969 (Previous Catalog # AAPP47112)
• Uniprot ID: P68133
• Protein Name: Actin, alpha skeletal muscle
• Protein Accession #: NP_001091
• Purification: Affinity Purified
• Nucleotide Accession #: NM_001100
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: ACTA1
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 100%; Rat: 100%
• Image 1: Human THP-1
  
  WB Suggested Anti-ACTA1 Antibody
  Titration: 1.0 ug/ml
  Positive Control: THP-1 Whole Cell
• Image 2: Mouse
  
  Lanes:
  Lane 1: 20ug mouse GL261 cell lysate
  Lane 2: 20ug mouse astrocyte cell lysate
  Primary Antibody Dilution:
  1:500
  Secondary Antibody:
  Anti-rabbit-HRP
  Secondary Antibody Dilution:
  1:500
  Gene Name:
  ACTA1
  Submitted by:
  Anonymous